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You have found 94 entries after clicking the GO button or a search link in a hot topic. Sorted by the main topic addressed, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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DOCUMENT 2014 HTM file
Time limiting opioid substitution therapy

Rather than being ‘parked’ on methadone, generally Britain’s heroin-addicted patients leave too soon to fully benefit, argue official government advisers on drug policy. Their report unambiguously countered concerns within the current UK government over methadone maintenance.

HOT TOPIC 2015 HTM file
Prescribing opiate-type drugs to opiate addicts: good sense or nonsense?

One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. For decades deeply felt and at times intemperate debate has surrounded a treatment which achieves unparalleled success by going with the grain of addiction, prescribing the same type of drug which opiate-dependent patients used illegally – a substitution castigated as surrender or hailed as an enlightened lifesaver.

STUDY 2010 HTM file
The SUMMIT Trial: a field comparison of buprenorphine versus methadone maintenance treatment

Compared to methadone, buprenorphine is more often chosen in a make-or-break attempt to divorce oneself from illicit opiates found the first large-scale study to compare the drugs in real-life conditions at a British opiate addiction maintenance treatment programme.

STUDY 2013 HTM file
Medically assisted recovery from opiate dependence within the context of the UK drug strategy: methadone and suboxone (buprenorphine-naloxone) patients compared

Opiate dependent patients in Scotland who opted for or were allocated to methadone sustained their abstinence from heroin as well as those on buprenorphine, but buprenorphine was far better at helping continuing heroin users cut back – suggestive, but the study’s constraints make the practice implications unclear.

STUDY 2010 HTM file
Challenges to antagonist blockade during sustained-release naltrexone treatment

Despite being motivated to sustain abstinence and implanted with a drug which should have blocked the effects of opiates, in Norwegian studies most opiate-dependent patients used opiates and about a quarter did so repeatedly.

STUDY 2010 HTM file
Retention in naltrexone implant treatment for opioid dependence

In Norway over half the opiate dependent patients implanted with the opiate blocking drug naltrexone opted for another implant after six months when the first had worn off, giving themselves a year in which to construct a life no longer reliant on the effects of heroin.

STUDY 2009 HTM file
Naltrexone implants after in-patient treatment for opioid dependence: randomised controlled trial

In the first randomised trial, implants which block opiate-type drugs for months helped heroin addicts in Norway avoid relapse after detoxification. If these or allied products gain a UK licence, they could help pave the way to abstinence for the minority of suitable addicts.

DOCUMENT 2017 HTM file
Drug misuse and dependence: UK guidelines on clinical management

Last published in 2007, there is no more important document for UK clinicians involved in treating problem drug use than the so-called ‘Orange guidelines’. This major update offers detailed guidance on the range of problems, settings and patients clinicians encounter, substantially informing judgements of what constitutes good medical practice.

REVIEW ABSTRACT 2009 HTM file
Peer-based addiction recovery support: history, theory, practice, and scientific evaluation

This monograph is likely to become the handbook for the growing peer-based recovery movement in the UK. For administrators, the approaches it reviews offer a way to reconcile decreasing per-patient resources with a policy agenda now focused on reintegration and recovery.

STUDY 2009 HTM file
Methadone patients in the therapeutic community: a test of equivalency

Are therapeutic communities incompatible with methadone maintenance? Not when staff have been prepared to accept and work with methadone patients and programmes adapted to accommodate them. Then patients stay as long and sustain abstinence from illegal drug use just as well as other residents.

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