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You have found 59 entries after clicking the GO button or a search link in a hot topic. Sorted by the main topic addressed, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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REVIEW 2015 HTM file
Risks and benefits of nalmefene in the treatment of adult alcohol dependence: a systematic literature review and meta-analysis of published and unpublished double-blind randomized controlled trials

‘A pill for every ill’ is the gist of the attacks levelled at nalmefene in the form of Selincro, a drug expected to extend the benefits of pharmacotherapy to drinkers not physically dependent or in need of detoxification – or for critics, to medicalise psychosocial dependence on shaky scientific grounds.

REVIEW 2013 HTM file
Metaanalysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?

Naltrexone and acamprosate both modestly curtail drinking among alcohol-dependent patients, but which is best in which circumstances and for which treatment goals? To find out this review compared the medications’ performance when separately benchmarked against a placebo, bringing to bear much more data than is available from the few trials which directly compared the two drugs.

REVIEW 2018 HTM file
Baclofen: its effectiveness in reducing harmful drinking, craving, and negative mood. A meta-analysis

With patchy evidence of the effectiveness of baclofen, and serious concerns about the medication’s safety, is it ‘premature’ for the muscle-relaxant to be prescribed as a treatment for alcohol use disorders?

STUDY 2010 HTM file
The effectiveness of brief intervention among injured patients with alcohol dependence: who benefits from brief interventions?

At a US emergency department, a brief conversation about the pros and cons of their risky drinking and offers of support for any efforts to reduce harm curbed drinking among alcohol-dependent patients; non-dependent patients tended to do better with assessment and usual care only.

STUDY 2010 HTM file
Ethnic differences in drinking outcomes following a brief alcohol intervention in the trauma care setting

At a US emergency department, a brief conversation about the pros and cons of their drinking and offers of support for any efforts to reduce harm led (compared to assessment and usual care) to extra reductions in the drinking of injured Hispanic patients but not white or black patients.

STUDY 2010 HTM file
The role of ethnic matching between patient and provider on the effectiveness of brief alcohol interventions with Hispanics

At a US emergency department, a brief conversation about the pros and cons of their risky drinking and offers of support for any efforts to reduce harm led to extra reductions in the drinking of Hispanic patients which were greatest when they were matched to a Hispanic and Spanish-speaking counsellor.

STUDY 2010 HTM file
Efficacy of physician-delivered brief counseling intervention for binge drinkers

In Madrid, unusually a primary care brief alcohol intervention targeted heavy episodic or 'binge' drinking. The result was drinking reductions which probably saved lives due to less drunkenness and less drinking overall – and both screening and intervention were done by the doctors themselves, not specialist staff.

STUDY 2012 HTM file
Text-message-based drinking assessments and brief interventions for young adults discharged from the emergency department

For the first time this US study tried mobile phone text messaging as a way to moderate the hazardous drinking of young adults screened at emergency departments. Compared to merely monitoring, text-based advice did cut drinking – but why did the monitoring-only patients actually start to drink more?

STUDY 2010 HTM file
A brief alcohol intervention for hazardously drinking incarcerated women

Could just two motivational interviewing sessions moderate the drinking of very heavy drinking US women prisoners? The surprise was not that there were few benefits, but that there were some, especially after the reinforcing session usually conducted after the prisoners' release.

STUDY 2014 HTM file
Web-based alcohol screening and brief intervention for university students: a randomized trial

Findings from this multi-university study in New Zealand seem an example of trials of brief alcohol interventions as they would be implemented in routine practice failing to match more promising findings from trials conducted in less ‘real world’ circumstances.


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