Effectiveness bank home page. Opens new window Hot topic search results

You have found 50 entries after clicking the GO button or a search link in a hot topic. Starting with the most recently added or updated entries, the list shows in orange the type of entry, year the original document was published (or if one of our own documents, the year last updated), and the type of file you will download when you click on the title. In blue is the document’s title followed by a brief description.

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REVIEW 2016 HTM file
A rapid evidence review of the effectiveness and cost-effectiveness of alcohol control policies: an English perspective

An ambitious attempt to use research to understand the most effective and cost-effective set of policies for reducing alcohol-related harm in the English context, from taxation and price regulation to managing the drinking environment.

REVIEW 2011 HTM file
Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence

This impressive assessment of what evaluation research means for alcohol dependence treatment in Britain is distinguished by reviews of the latest literature on the sub-topics it covers; in some cases these starkly reveal the inadequacies of the evidence base.

STUDY 2014 HTM file
Effectiveness of training family physicians to deliver a brief intervention to address excessive substance use among young patients: a cluster randomized controlled trial

Can a brief intervention delivered by trained GPs impact on young patients’ excessive drinking and cannabis use? Set in French-speaking Switzerland, this study examines outcomes over a 12-month period.

HOT TOPIC 2017 HTM file
Should dependent drinkers always try for abstinence?

One of our hot topics offering background and analysis on important issues which sometimes generate heated debate. For decades no issue has been hotter than whether dependent drinkers should always be advised to aim for abstinence rather than controlled drinking. We detail the fascinating background to this question faced on entering treatment by every drinker and their counsellor.

REVIEW 2013 HTM file
Metaanalysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?

Naltrexone and acamprosate both modestly curtail drinking among alcohol-dependent patients, but which is best in which circumstances and for which treatment goals? To find out this review compared the medications’ performance when separately benchmarked against a placebo, bringing to bear much more data than is available from the few trials which directly compared the two drugs.

STUDY 2015 HTM file
Navigating the alcohol treatment pathway: A qualitative study from the service users’ perspective

Patient interviews provide insight into low levels of engagement and retention in alcohol treatment services, hindering the effective provision of treatment for dependent drinkers. Findings suggest that treatment pathways should better reflect the capacity and capabilities of people with alcohol dependence.

REVIEW 2012 HTM file
Behavioral counseling after screening for alcohol misuse in primary care: a systematic review and meta-analysis for the U.S. Preventive Services Task Force

Amalgamated findings from studies of risky drinkers identified and counselled in primary care settings indicate that compared to screening and assessment only, brief counselling lead to greater reductions in drinking, gains reflected less strongly in some indicators of health. However, it is unclear whether the generally small impacts would be sustained in routine practice.

REVIEW 2015 HTM file
Risks and benefits of nalmefene in the treatment of adult alcohol dependence: a systematic literature review and meta-analysis of published and unpublished double-blind randomized controlled trials

‘A pill for every ill’ is the gist of the attacks levelled at nalmefene in the form of Selincro, a drug expected to extend the benefits of pharmacotherapy to drinkers not physically dependent or in need of detoxification – or for critics, to medicalise psychosocial dependence on shaky scientific grounds.

REVIEW 2015 HTM file
The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence, Europe versus the rest of the world: a meta-analysis

Whether differences between the patients mean impacts of the alcohol treatment medications acamprosate and naltrexone vary between Europe and the USA was the issue which motivated this fresh analysis of randomised trials. It confirmed the medications’ efficacy and found no evidence that this differed in European trials versus those conducted elsewhere.

STUDY 1997 HTM file
Performance contracting for substance abuse treatment

This US study finds that performance contracting may be associated with improvements in service utilisation and treatment outcomes, but does not appear to increase engagement with under-served populations.


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